While lower-depend MBL almost never progresses to CLL, superior-count MBL progresses to CLL requiring therapy in a rate of 1% to two% annually. Superior-rely MBL is distinguished from Rai 0 CLL depending on whether or not the B-mobile rely is above or underneath five × 109/L. Even though folks with equally higher-depend MBL and CLL Rai stage 0 are